Correction: 1:43 The left side of the graph should be labeled as Celsius, and the right side should be labeled as Fahrenheit.

Link to survey: http://to.pbs.org/2022Survey

Ethylene glycol is the most common ingredient in automotive antifreeze. But for years it was used in homicidal poisonings. What made this household chemical so dangerous? And why is it no longer a viable poison?
#chemistry #poison #antifreeze

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Reactions is a production of the American Chemical Society.
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Sources:
Intentional Ethylene Glycol Poisoning Increase after Media Coverage of Antifreeze Murders
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117604/

Woman pleads guilty to killing husband with antifreeze
https://www.delawareonline.com/story/news/local/2017/02/06/woman-pleads-guilty-killing-husband-antifreeze/97544316/

Homicidal Ethylene Glycol Intoxication
https://journals.lww.com/amjforensicmedicine/Abstract/2006/06000/Homicidal_Ethylene_Glycol_Intoxication__A_Report.11.aspx

Ethylene glycol poisoning: Quintessential clinical toxicology; analytical conundrum
https://www.sciencedirect.com/science/article/abs/pii/S000989811100595X#

Ethylene Glycol Toxicity
https://www.ncbi.nlm.nih.gov/books/NBK537009/

Alcohol Dehydrogenases
https://www.sciencedirect.com/topics/chemistry/alcohol-dehydrogenases

Why Is Antifreeze So Delicious?
https://slate.com/news-and-politics/2004/07/why-is-antifreeze-so-delicious.html

Bitter and sweet components of ethanol taste in humans
https://pubmed.ncbi.nlm.nih.gov/10940547/

Alcohol Metabolism: An Update
https://pubs.niaaa.nih.gov/publications/aa72/aa72.htm

Biochemistry, Lactate Dehydrogenase
https://www.ncbi.nlm.nih.gov/books/NBK557536/

Signal transduction and information processing in mammalian taste buds
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723147/

What Are the Toxicological Effects of Ethylene Glycol Poisoning?
https://www.atsdr.cdc.gov/csem/ethylene-propylene-glycol/toxicological_effects.html#:~:text=Ethyleneglycolisacentral,causeseriousorfataltoxicity

Antifreeze and Engine Coolant Being Bittered Nationwide
https://web.archive.org/web/20121228225407/http://www.cspa.org/news-media-center/news-releases/2012/12/antifreeze-and-engine-coolant-being-bittered-nationwide

The impact of bittering agents on pediatric ingestions of antifreeze
https://pubmed.ncbi.nlm.nih.gov/19571333/

The impact of bittering agents on suicidal ingestions of antifreeze
https://pubmed.ncbi.nlm.nih.gov/18584362/

Toxicology of E-Cigarette Constituents
https://www.ncbi.nlm.nih.gov/books/NBK507184/

Food additive could serve as a safer, more environmentally friendly antifreeze
https://www.eurekalert.org/news-releases/554583