Does Sugar Cause Diabetes?

If you have diabetes, you have way too much sugar in your bloodstream. So does eating a lot of sugar cause it?

#diabetes #bloodsugar #insulin

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Executive Producers:
George Zaidan
Hilary Hudson

Andrew Sobey
Elaine Seward

Sam Jones, PhD

Scientific consultants:
Thomas Delong, PhD
Leila Duman, PhD
Peter Havel, DVM, PhD
Katie Page, MD
Brianne Raccor, PhD
Kimber Stanhope, PhD

Consumption of sugar-sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fraction

Sugar-Sweetened Beverages and Risk of Metabolic Syndrome and Type 2 Diabetes

A Prospective Study of Sugar Intake and Risk of Type 2 Diabetes in Women

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Sugar and diabetes

Reiser, S., et al., Isocaloric exchange of dietary starch and sucrose in humans. II. Effect on fasting blood insulin, glucose, and glucagon and on insulin and glucose response to a sucrose load. Am J Clin Nutr, 1979. 32(11): p. 2206-16.

Hallfrisch, J., et al., Effects of dietary fructose on plasma glucose and hormone responses in normal and hyperinsulinemic men. J Nutr, 1983. 113(9): p. 1819-26.

Reiser, S., et al., Serum insulin and glucose in hyperinsulinemic subjects fed three different levels of sucrose. Am J Clin Nutr, 1981. 34(11): p. 2348-58.

Schwarz, J.M., et al., Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat. J Clin Endocrinol Metab, 2015. 100(6): p. 2434-42.

Aeberli I, Hochuli M, Gerber PA, Sze L, Murer SB, Tappy L, Spinas GA, Berneis K. Moderate amounts of fructose consumption impair insulin sensitivity in healthy young men: a randomized controlled trial. Diabetes Care. 2013 Jan;36(1):150-6.

Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ. Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J Clin Invest. 2009 May;119(5):1322-34.

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