Can Science Make Less Addictive Opioids?

Will we ever have painkillers as good as opioids, but without the risk of addiction and overdose?

#opioids #heroin #opioidcrisis

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Executive Producers:
George Zaidan
Hilary Hudson

Andrew Sobey
Elaine Seward

Sam Jones, PhD

Scientific consultants:
Michelle Boucher, PhD
Kelly Dunn, PhD
Leila Duman, PhD
Kim Janda, PhD

Frederich Serturner

Opioid toxicity

Opioid overdoses–world stats,Worldwideabout0.5milliondeathsareattributabletodruguse,ofopioidoverdosein2017

Opioid death rates in the US,in2018with46802deaths.

Inside the Story of America’s 19th-Century Opiate Addiction

Abuse-deterrent opioids

NIH solicits research into vaccines that protect against opioid use

Vaccines against addictive drugs push forward despite past failures

Looking beyond opioids for safer pain relief

Opioid abuse timeline (FDA)

Overdose death rates,in2018with46802deaths.


God’s Own Medicine




Heroin chapter

Structure of ibuprofen bound to COX-2

Use of Oxycodone in Pain Management,marketin1996(2).

Overcoming opioids: The quest for less addictive drugs

Rats prefer sugar to heroin

NIDA heroin info

Heroin History

Frontline PBS: Opium throughout history

The Ongoing Opioid Prescription Epidemic: Historical Context

Heroin’s Addiction’s Fraught History

Heroin Prescription and History

Addiction medications

Opiate history

Death Tolls

Overdose Increases


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